Snapshots of metabolic phenotypes

Snapshots of Systems - Metabolic Control Analysis and Biotechnology

Metabolic Phenotypes in Pancreatic Cancer

INTRODUCTION The aim of present study was to profile the glucose-dependent and glutamine- dependent metabolism in pancreatic cancer. METHODS We performed Immunohistochemical staining of GLUT1, CAIX, BNIP3, p62, LC3, GLUD1, and GOT1. Based on the expression of metabolism-related proteins, the metabolic phenotypes of tumors were classified into two categories, including glucose- and glutamine-d...

Evidence of different metabolic phenotypes in humans.

The study of metabolic responses to drugs, environmental changes, and diseases is a new promising area of metabonomic research. Metabolic fingerprints can be obtained by analytical techniques such as nuclear magnetic resonance (NMR). In principle, alterations of these fingerprints due to appearance/disappearance or concentration changes of metabolites can provide early evidences of, for example...

Metabolic syndrome and different obesity phenotypes in the elderly women population: Iran’s Health System on aging

Background: Current literature has been focused on types of obesity with normal BMI (body mass index), but metabolically unhealthy.This study evaluates the prevalence of metabolical phenotypes of obesity. We also identified the best obesity index in predicting the components of metabolic syndrome (MetS). Methods: A cross-sectional study has been conducted on 164 women over 60 years. Anthropome...

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